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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIBCH
All Species:
20.61
Human Site:
S258
Identified Species:
32.38
UniProt:
Q6NVY1
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NVY1
NP_055177.2
386
43482
S258
S
K
I
D
R
D
K
S
F
I
L
E
E
H
M
Chimpanzee
Pan troglodytes
XP_515988
440
48807
S312
S
K
I
D
R
D
K
S
F
I
L
E
E
H
M
Rhesus Macaque
Macaca mulatta
XP_001103467
444
49874
S316
S
K
I
D
R
D
K
S
F
M
L
E
E
H
M
Dog
Lupus familis
XP_848689
359
39946
K240
I
L
E
E
H
M
D
K
I
N
S
W
F
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZS1
385
43019
S257
S
K
M
D
Q
D
K
S
I
I
F
E
E
H
M
Rat
Rattus norvegicus
Q5XIE6
385
43006
S257
S
K
M
G
Q
D
K
S
I
I
F
E
E
H
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJ60
385
42810
E257
T
K
I
D
Q
E
K
E
F
V
L
D
E
H
M
Frog
Xenopus laevis
A2VDC2
385
42348
P257
S
Y
A
A
Q
D
K
P
F
V
L
A
E
N
M
Zebra Danio
Brachydanio rerio
Q58EB4
382
42258
P254
S
H
L
D
A
E
K
P
F
V
L
Q
E
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650453
385
42729
V262
K
P
F
S
L
Q
P
V
L
E
Q
I
N
K
N
Honey Bee
Apis mellifera
XP_396249
396
44074
Y263
Q
E
F
C
L
A
P
Y
M
S
K
I
D
K
Y
Nematode Worm
Caenorhab. elegans
P34559
288
31153
P169
E
I
N
I
G
T
I
P
G
A
G
G
T
Q
R
Sea Urchin
Strong. purpuratus
XP_791196
379
41899
P251
C
S
I
D
A
D
K
P
F
S
L
A
P
H
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q1PEY5
378
42237
T255
S
A
L
E
R
E
V
T
Q
K
P
N
D
W
L
Baker's Yeast
Sacchar. cerevisiae
P28817
500
56270
S261
F
F
G
M
V
N
E
S
I
D
E
F
V
S
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.8
84.9
84.4
N.A.
81.8
81.6
N.A.
N.A.
69.1
69.6
65.2
N.A.
49.2
47.9
24.6
56.9
Protein Similarity:
100
86.8
86.2
87.8
N.A.
92.2
92.2
N.A.
N.A.
83.9
81.3
78.2
N.A.
67.6
67.1
40.9
75.1
P-Site Identity:
100
100
93.3
0
N.A.
73.3
66.6
N.A.
N.A.
60
46.6
40
N.A.
0
0
0
46.6
P-Site Similarity:
100
100
100
6.6
N.A.
86.6
80
N.A.
N.A.
93.3
66.6
66.6
N.A.
0
13.3
0
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.1
30.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.8
47
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
7
14
7
0
0
0
7
0
14
0
0
7
% A
% Cys:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
47
0
47
7
0
0
7
0
7
14
0
0
% D
% Glu:
7
7
7
14
0
20
7
7
0
7
7
34
54
0
0
% E
% Phe:
7
7
14
0
0
0
0
0
47
0
14
7
7
0
0
% F
% Gly:
0
0
7
7
7
0
0
0
7
0
7
7
0
0
0
% G
% His:
0
7
0
0
7
0
0
0
0
0
0
0
0
47
0
% H
% Ile:
7
7
34
7
0
0
7
0
27
27
0
14
0
0
0
% I
% Lys:
7
40
0
0
0
0
60
7
0
7
7
0
0
14
7
% K
% Leu:
0
7
14
0
14
0
0
0
7
0
47
0
0
0
7
% L
% Met:
0
0
14
7
0
7
0
0
7
7
0
0
0
0
47
% M
% Asn:
0
0
7
0
0
7
0
0
0
7
0
7
7
7
7
% N
% Pro:
0
7
0
0
0
0
14
27
0
0
7
0
7
0
7
% P
% Gln:
7
0
0
0
27
7
0
0
7
0
7
7
0
14
0
% Q
% Arg:
0
0
0
0
27
0
0
0
0
0
0
0
0
0
7
% R
% Ser:
54
7
0
7
0
0
0
40
0
14
7
0
0
14
0
% S
% Thr:
7
0
0
0
0
7
0
7
0
0
0
0
7
0
7
% T
% Val:
0
0
0
0
7
0
7
7
0
20
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
0
% W
% Tyr:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _